Forcing FAK into Transcriptional Activity

Forcing mycoplasma mobile into line.

public order and forcing one to enter into contract

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Planar Polarity: Forcing Cells Into Line

Polarisation of tissues in the plane of an epithelium is fundamental for both animal morphogenesis and organ function. A new paper describes a role for mechanical cues in determining how such polarity is aligned with the body axes.

Coding into K by Reasonable Forcing

We present a technique for coding sets “into K,” where K is the core model below a strong cardinal. Specifically, we show that if there is no inner model with a strong cardinal then any X ⊂ ω1 can be made ∆3 (in the codes) in a reasonable and stationary preserving set generic extension.

Inhibition of FAK kinase activity preferentially targets cancer stem cells

Because cancer stem cells (CSCs) have been implicated in chemo-resistance, metastasis and tumor recurrence, therapeutic targeting of CSCs holds promise to address these clinical challenges to cancer treatment. VS-4718 and VS-6063 are potent inhibitors of focal adhesion kinase (FAK), a non-receptor tyrosine kinase that mediates cell signals transmitted by integrins and growth factor receptors. W...